It’s almost as though cruelty and neglect can affect people’s mental health.
Everyone gives Batman shit over the state of Arkham but no one ever talks about Iron Heights.
There was a bit of criticism for Iron Heights within the Flash book, such as when Ashley Zolomon called the prison “the Rogue Factory” (which she said was a widespread nickname) and accused Wolfe of having no compassion for its prisoners. It seems quite likely that the mistreatment there has made some of the prisoners worse, with I think Roscoe as one of the prime examples. And as awful as Arkham is, at least they make some attempt to treat their inmates; we’ve seen that Iron Heights leaves theirs barefoot in straitjackets and isolated in filthy cells. So it’s no surprise that they end up even more mentally ill and anti-social, which is almost certainly what Ashley was alluding to.
Wally and Wolfe clashed on a number of occasions over the treatment of prisoners there, once Wally found out about it. But Wally had no authority there, he was just a vigilante super-hero, and Wolfe kept running things the way he wanted to. The one win I remember was that Wally was able to get Fallout an actual, comfortable room that absorbed his radiation instead of leaving him hooked up to tubes like he was before.